Deposition studies of aerosol delivery by nasal cannula to infants
نویسندگان
چکیده
منابع مشابه
Intermittent aerosol delivery to the lungs during high-flow nasal cannula therapy.
INTRODUCTION Use of submicrometer particles combined with condensational growth techniques has been proposed to reduce drug losses within components of high-flow nasal cannula therapy systems and to enhance the dose reaching the lower respiratory tract. These methods have been evaluated using continuous inhalation flow rather than realistic inhalation/exhalation breathing cycles. The goal of th...
متن کاملIn vitro comparison of heliox and oxygen in aerosol delivery using pediatric high flow nasal cannula.
Drug administration via high flow nasal cannula (HFNC) has been described in pediatrics but the amount of albuterol delivery with an HFNC is not known. The purpose of this study is to quantify aerosol delivery with heliox and oxygen (O(2)) in a model of pediatric ventilation. A vibrating mesh nebulizer (Aeroneb Solo, Aerogen) was placed on the inspiratory inlet of a heated humidifier and heated...
متن کاملAerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula.
Noninvasive ventilation (NIV) and high-flow nasal cannula (HFNC) are increasingly used for patients with acute respiratory failure. Some patients receiving these therapies might also benefit from inhaled drug delivery. Thus, it is attractive to combine aerosol therapy with NIV or HFNC. The purpose of this paper is to review the available evidence related to the use of inhaled aerosols with NIV ...
متن کاملAerosol Drug Delivery for Infants
INTRODUCTION Every year, approximately 2,500 children are admitted to the pediatric intensive care unit (PICU) at the Children’s Hospital of Pittsburgh at the University of Pittsburgh Medical Center alone [1]. Respiratory illnesses are one of the leading causes of admission [1]. For children with acute respiratory illnesses, inhaled medications are a common method of treatment, as this allows p...
متن کاملHigh-flow nasal cannula therapy for infants with bronchiolitis.
BACKGROUND Bronchiolitis is a common lower respiratory tract illness, usually of viral aetiology, affecting infants younger than 24 months of age and is a frequent cause of hospitalisation. It causes airway inflammation, mucus production and mucous plugging, resulting in airway obstruction. Effective pharmacotherapy is lacking and bronchiolitis is a major cause of morbidity and mortality.Conven...
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ژورنال
عنوان ژورنال: Pediatric Pulmonology
سال: 2019
ISSN: 8755-6863,1099-0496
DOI: 10.1002/ppul.24326